About OncoVariant


OncoVariant supports physicians in interpreting the genetic alterations of their cancer patients. BioVariance has developed a web-based platform to identify the most suitable medication based on the patient’s own genetic variants. Any manual search for the most effective medication is inherently time consuming and complicated, especially for off-label drugs. OncoVariant supports and simplifies this process by automatically comparing and analyzing patient variants with publicly available databases regarding treatment options. The results are combined in a comprehensive report containing information about different gene variants, appropriate clinical studies and other evidence as well as information on the drug substances and their interactions. OncoVariant saves significant time in the identification and analysis of suitable therapy options by analyzing several gene variants simultaneously and providing a high-quality and professionally documented overview of best practice treatment. Quickly identify which genetic changes require which type of medication! OncoVariant enables personalized patient therapy while minimizing time and effort on behalf of attending physicians. You can upload a VCF file or single variants to the platform. The platform accesses databases CGI and CIViC as well as several other databases (DGIdb, CPIC, EMA and the National Library of Medicine) that are used for a comparison of the literary sources regarding the requested variants. The analysis can be focused further by specifying the specific type of the cancer.

The benefits at a glance

Scientifically profound knowledge

Time saving by automated search

Personalized treatment for your patient

User-friendly and simple handling

Safe and encoded data transmission

Avoid side effects and needless treatment

The examination of numerous information from high-quality databases ensures the high value of the proposed therapy options.

  • Therapeutic options based on individual genetic variants
  • Evidence of the clinical relevance of genetic variations
  • Classification in driver, passenger and other mutations
  • Interactions of drugs
  • General information on drugs (e.g. approval)

Example of used databases

Start using OncoVariant

In 4 steps to your therapeutic success

Click on the button “Order Now“ and fill in the form


We will send you the software license agreement, please sign it


We will send you an e-mail with your access data


You can start using OncoVariant immediatelly


Complete interpretation of genetic data as a service

We can gladly take over the complete analysis of the genetic data for you.​

If desired, we can expand this service by ​

  • more intensive manual research, e.g. on not yet published studies​
  • preparation of the results for patients or non-medical professionals​

We would be pleased to create an individual offer for you, please contact us at info@oncovariant.com.

News and Updates

OncoVariant automates the drug search for oncologists

Waldsassen – BioVariance has finished the development of the platform “OncoVariant” for the interpretation of genetic variants in cancer patients. Thereby, the crucial search for READ MORE

Colorectal cancer - the evil within

The facts "Coloreactal carcinoma" means several malignant tumor types in the colon or rectum. Malignant tumors rarely occur in other intestinal areas like small intestine or caecum READ MORE

Off label use in paediatrics

Generally, drugs are only allowed to be prescribed when special agencies have tested them on safety, effectiveness and quality and have approved them on corresponding indications. READ MORE

Colorectal cancer therapies

Waldsassen – BioVariance has received a commitment for the project “REVERT” from the European Commission as part of “HORIZON 2020”, the EU framework program for research and innovation. READ MORE

The global burden of cancer

Many people wonder why there is still no cure for cancer yet. But cancer isn’t just one disease. It is more than 100 diseases, and each of these types is divided into several sub-types. READ MORE

Omic tools

The rapid advances in cutting-edge technologies and informatics tools utilized in biomedical science to generate and process high-throughput biological datasets have finally spread into various economic sectors. READ MORE

The fight against breast cancer

Due to great progress regarding early cancer diagnosis, diagnostics, therapy and care in the last decades, the survival rate and quality of life of patients suffering from breast cancer increased significantly in Germany. READ MORE

Multiresistant bacteria

Regular clinical tests demonstrate a serious and growing threat today: resistant bacteria showing immunity against many common antibiotics. The evolution and widespread distribution of antibiotic resistanct pathogens has made READ MORE

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About us

BioVariance was founded by Dr. Josef Scheiber in 2013. A multidisciplinary team consisting of software developers and biologists develops innovative AI solutions for precision medicine.

We focus on complex biomedical data analyses and customized software development for the pharmaceutical, biotechnology and healthcare sector.

We offer bioinformatics services in the fields of drug development, biomarker and target identification as well as translational and personalized medicine.

Our customers are renowned pharma companies as well as global academical institutes which act in the area of R&D, preclinical/clinical trials and precision medicine.

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